A Phase 1, Study of BMF-500 in Adults With Acute Leukemia

Active:	Yes
Cancer Type:	Leukemia	NCT ID:	NCT05918692
Trial Phases:	Phase I	Protocol IDs:	COVALENT-103 (primary) NCI-2023-06835
Eligibility:	18 Years and older, Male and Female	Study Type:	Treatment
Study Sponsor:	Biomea Fusion Inc.
NCI Full Details:	http://clinicaltrials.gov/show/NCT05918692

Summary

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral
FLT3 inhibitor, in adult patients with acute leukemia.

Objectives

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral
covalent FLT3 inhibitor, in adult patients with acute myeloid leukemia (AML), acute
lymphocytic leukemia (ALL) and Acute Mixed-Phenotype Leukemia (MPAL) who may or may not
be on Antifungals.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
404-778-5180
winshipcancer.emory.edu

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